Table 1 Associations between MASLD as time-varying exposures and subsequent PDAC as the outcome

From: Metabolic dysfunction-associated steatotic liver disease accelerates pancreatic cancer progression and metastasis via the macrophage migration inhibitory factor-CD44 axis

 

Hazard ratio (95% CI)

P value

MASLD exposure (time varying)

MASLD

  

Model 1a

4.28 (3.31, 5.53)

<0.0001

Model 2b

3.73 (2.88, 4.82)

<0.0001

Model 3c

3.48 (2.69, 4.50)

<0.0001

  1. CI confidence interval, TG triglycerides
  2. aModel 1, adjusted for sex, age, and Townsend deprivation index
  3. bModel 2, included covariates from model 1 plus drinking status, smoking status, body mass index
  4. cModel 3, included covariates from model 2 plus TG, history of hypertension and history of diabetes
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