Fig. 8 | Signal Transduction and Targeted Therapy

Fig. 8

From: Extraocular delivery of bioswitchable tri-miR-22-loaded tetrahedral DNA nanostructures for intraocular neovascular and neurodegenerative repair

Fig. 8

Subconjunctival BiRDS protects retinal neural function in an OIR mouse model. a Schematic of retinal functional assessment in mice via scotopic and photopic electroretinograms (ERGs). b Representative scotopic ERGs (1.0 cd·s/m2), oscillatory potentials (Ops) (3.0 cd·s/m2), and photopic ERGs (10.0 cd·s/m2) are shown. c Bar plots showing the statistical analysis of the wave amplitudes and latency times for the a-waves and b-waves of scotopic ERGs and the a-waves and b-waves of photopic ERGs and OPs. Mean ± SD. n = 6. *p < 0.05, **p < 0.01, ****p < 0.0001

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