Fig. 8 | Signal Transduction and Targeted Therapy

Fig. 8

From: Spi-1 proto-oncogene regulates mRNA hypertranscription and malignant progression in head and neck cancer

Fig. 8The alternative text for this image may have been generated using AI.

Elevated SPI1 expression is associated with poor prognosis in laryngeal and hypopharyngeal cancer patients. a Validation of SPI1 expression in a local cohort of laryngeal cancer patients. b Kaplan‒Meier survival curve and c multivariate Cox forest plot for laryngeal cancer patients. d Validation of SPI1 expression in a local cohort of hypopharyngeal cancer patients. e Kaplan‒Meier survival curve and f multivariate Cox forest plot for hypopharyngeal cancer patients. For Kaplan‒Meier analyses (b, e), follow-up was truncated at 1000 days to ensure stable risk set sizes and avoid overinterpretation of sparse late follow-up

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