Fig. 4
From: Guidelines for the conduct of clinical trials in spinal cord injury: Neuroimaging biomarkers
The relationship between the sample size required for a 6-month randomised clinical trial to detect a 100% treatment effect with 80% statistical power and 5% significant differences between healthy controls and patient group for a cross-sectional cord area and b cranial corticospinal tract (CST) volume. The calculations cover a range of plausible baseline vs. 6-month correlations around the observed patient values of 0.99
