Fig. 1: A representative participant’s T2-weighted MRI.

The left panel shows the mid-sagittal image with the lesion hyperintensity observed. The middle panel shows consecutive axial slices through the damage, with the lesion hyperintensity segmented in red and the surrounding spinal cord segmented in blue. The calculated axial damage ratios are seen in the right panel, with the cranial-most axial slice demonstrating the maximum axial damage ratio used for statistical analysis.