Abstract
Study design
Pre-post, pilot study.
Objectives
To characterize ventilatory (VE) responses to exercise following warm-up walking in individuals with chronic incomplete spinal cord injury (iSCI) during constant work rate (CWR) exercise. Secondarily, to investigate VE and tidal volume (VT) variability, and ratings of perceived exertion (RPE) before and after overground locomotor training (OLT).
Setting
Research laboratory.
Methods
A 6-min CWR walking bout at preferred pace was used as a warm-up followed by 6 min of rest and a second 6-min CWR bout at above preferred walking pace. The second CWR bout was analyzed. Breath-by-breath ventilatory data were examined using a curvilinear least squares fitting procedure with a mono-exponential model. VE and VT variability was calculated as the difference between the observed and predicted values and RPE was taken every 2 min.
Results
Participants (n = 3, C4–C5) achieved a hyperpneic response to exercise in VE and VT. OLT resulted in faster ventilatory kinetics and reductions of 24 and 29% for VE and VT variability, respectively. A 30% reduction in RPE was concurrent with the reductions in ventilatory variability.
Conclusions
OLT may improve ventilatory control during CWR in patients with cervical motor-iSCI. These data suggest that in some participants with iSCI, ventilation may influence RPE during walking. Future research should investigate mechanisms of ventilatory variability and its implications in walking performance in patients with iSCI.
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Data availability
Data was collected prior to 2018 in which we were not required to enter data into an archive.
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All study procedures were approved by the Institutional Review Board at George Mason University (618911). The study conformed to the standards set by the Declaration of Helsinki, except for registration in a public database. All participants provided written consent prior to enrollment in the study.
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Panza, G.S., Herrick, J.E., Chin, L.M. et al. Effect of overground locomotor training on ventilatory kinetics and rate of perceived exertion in persons with cervical motor-incomplete spinal cord injury. Spinal Cord Ser Cases 5, 80 (2019). https://doi.org/10.1038/s41394-019-0223-7
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DOI: https://doi.org/10.1038/s41394-019-0223-7
