Fig. 2
Cumulative relative abundance of sequences with similarity to ORFs encoded by ɸB124-14, Cyanophage SYN5 and Burkholderia phage KS10 in assembled whole community metagenomes. Data sets were searched using translated ɸB124-14, ɸSYN5 or ɸKS10 ORF sequences using tBlastn. Valid hits were used to calculate the cumulative relative abundance sequences with similarity to phage ORFs in each data set (expressed as Hits/Mb). a–c Relative representation of phage ORFs across habitats represented by whole community metagenomes. Charts show cumulative relative abundance of sequences with similarity to ORFs encoded by Bacteroides ɸB124-14, Cyanobacteria ɸSYN5 and Burkholderia ɸKS10. d–g Comparison of phage representation within specific habitats. Charts show cumulative relative abundance of sequences with similarity to ORFs from each phage examined in whole community metagenomes from the human gut, human oral cavity (mouth and throat), other human body sites (skin, nares and vagina), non-human gut and wider environment. For all data sets, bars show mean plus SEM. ***P < 0.001, ****P < 0.0001 vs. environmental viromes (a–c) or ɸB124-14 (d–g)
