Fig. 5

Lower ligand structure predictions. a, b Proportion of genomes containing the indicated lower ligand structure determinants (inner circle), α-ribazole salvaging gene (inner ring), and corrinoid remodeling gene (outer ring) in the complete filtered data set separated by cobamide producer category (a) and in cobamide producers separated by phylum (b). c. The anaerobic benzimidazole biosynthesis pathway is shown with the functions that catalyze each step above the arrows. The genes required to produce each benzimidazole are shown below each structure, with the number of genomes in the complete filtered data set containing each combination of genes in parentheses. The sets of bza genes that do not have a predicted structure are listed on the right. Aminoimidazole ribotide (AIR), 5-hydroxybenzimidazole (5-OHBza), 5-methoxybenzimidazole (5-OMeBza), 5-methoxy-6-methylbenzimidazole (5-OMe-6-MeBza)