Fig. 2

Genome streamlining in Methylophilaceae. Significant relationships between genome sizes (Mbp) and genomic GC content (%), lengths of intergenic spacers (bp), coding density (%), mean CDS length (bp), overlapping CDS (%), number of paralogs, histidine kinases, and sigma factors, and significant relationships between genomic GC content (%) and TAA stop codon, TAG stop codon, lysine, and arginine usage (%) and C, N, and S atoms per amino acid (mol%)