Fig. 3
Metabolic modules in Methylophilaceae. Presence of selected metabolic modules in Methylophilaceae strains. For details on phylogenomic tree see Figs. 1 and S1, for details on pathways see Table S4. T4SS: type 4 secretion system; MOX-PQQ: methanol oxidation and pyrroloquinoline quinone biosynthesis; XoxF/MxaF: methanol dehydrogenase XoxF/MxaF; NMG: N-methyloglutamate pathway; MADH: methylamine dehydrogenase; FaDH: formaldehyde dehydrogenase; H4F-folD: H4-linked formaldehyde oxidation, folD form; H4MPT: H4MPT-linked formaldehyde oxidation; FOX: formate oxidation; RuMP: ribulose monophosphate cycle; ass. NO3 reduction: assimilatory nitrate reduction; diss. NO3 reduction: dissimilatory nitrate reduction; ass. SO4 reduction: assimilatory sulfate reduction; NDH-dehydrogenase: H+-translocating NADH:quinone oxidoreductase; NQR-dehydrogenase: Na+-translocating NADH:quinone oxidoreductase; DtpD: dipeptide/tripeptide permease DtpD; AlsT: sodium:alanine symporter AlsT; ActP: sodium:acetate symporter ActP; GltT: sodium:dicarboxylate symporter GltT; NhaP2: sodium:proton antiporter NhaP2; NhaE-like: sodium:proton antiporter NhaE; AA transporter: amino acid transporters; fructose PTS: fructose-specific phosphotransferase system; MCA: methylcitric acid cycle
