Fig. 4: Distribution of transposon-insertion sites in the Dictyostelium discoideum-trapped Mycobacterium bovis mutant pool.

a The distribution of transposon-insertion sites around the bacterial chromosome that result in defective transit through D. discoideum are depicted in the outer ring (in blue). The line length represents the fold change after 2-day infection in D. discoideum, compared with the inoculum. The distribution of essential growth genes is represented by the inner ring (rust). b The distribution of mutations associated with defective transit through D. discoideum is displayed by functional class (outer ring). The distribution of genes containing transposon insertions in the unselected inoculum library is represented by the inner circle.