Fig. 4: Relative abundance of ahOTUs across three clusters.
a, b Relative abundance of ahOTUs in three clusters summarized in a ternary plot. Each vertex represents one of the three clusters. Each circle represents an ahOTU. The position of a circle is determined by relative abundance (RA) of the ahOTU in three clusters, and the circle size is proportional to the ahOTU’s average relative abundance across all 69 samples. In a, ahOTUs with significantly higher abundance in Cluster 1, 2, or 3 than in the other two clusters are colored in green, orange and brown, respectively, while OTUs without significant difference in abundance are shown in gray. In b, the circles are colored according to the taxonomic assignment of the ahOTUs. c–e Aggregated relative abundances (aRA) of ahOTUs with significantly higher abundance in one cluster across each of the three clusters. Each point represents an ahOTU. For each OTU its aRA in a cluster i (i = 1, 2, 3) is defined as \(aRA_i = \frac{{RA_i}}{{\mathop {\sum }\nolimits_{j = 1}^3 \left( {RA_j} \right)}}\), where RAi is the relative abundance of the ahOTU in the cluster i. The distribution of aRAs within a cluster is summarized by a probability density function and a box-and-whisker plot, with whiskers extending to 1.5 of the interquartile range.
