Fig. 8: Functional analysis of the three BPs. | The ISME Journal

Fig. 8: Functional analysis of the three BPs.

From: Inter-kingdom interactions and stability of methanogens revealed by machine-learning guided multi-omics analysis of industrial-scale biogas plants

Fig. 8: Functional analysis of the three BPs.

A Heatmap of the most active KEGG modules. Shown are the top 30 KEGG modules from all twelve samples based on metatranscriptomic data (shown in TPM). B Principal component analysis of KEGG module functional data. Each symbol is related to a specific BP-sample pair. C Significantly different methanogenic genes identified in the five most active methanogens. Shown are differences considered to be statistically significant as calculated by DESeq2 (i.e., with log2 FC > 2.0, p < 0.05). The heat map depicts the average gene activity of each methanogen in the various BPs. The blanks represent genes that were not significantly different in the provided methanogen, or the indicated gene is absent in the given nrMAG.

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