Fig. 3
Evaluating relevance of pharmacogenomics workflow. Capturing real world reported drug response population differentiation cases: left-vertical axis shows the Z-scores of the respective drug in the specific population pair that is most similar to the population pair reported in the literature. Diamonds represent the specific drug Z-score in the specific population pair. Dark red diamond indicates Z-score > 2.58 while light red diamond indicates Z-score < 2.58. The red shaded area shows the difference between the highest and lowest Z-scores for that drug. Right-vertical axis shows the highest and lowest FST scores of the top pf-pdSNPs in the specific drug pathway and they are represented by black and grey dots, respectively. Numbers correspond to the specific population pairs used for analyses and reported in literature
