Table 3 Multivariable logistic regression assessing association between SLCO1B1*5 genotype presence and non-senile cataract diagnosis in the on-statin cohort.

From: SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort

 

OR

CI

P value

SLCO1B1*5

0.7

0.5–0.9

0.007

Dyslipidaemia

1.7

1.4–2.0

2.3e−10

Obesity

1.2

1.0–1.4

0.02

Hypertension

1.9

1.6–2.2

7.1e−12

CKD

1.3

1.1–1.5

0.0006

PVD

1.2

0.8–1.6

0.3

Diabetes

2.0

1.7–2.3

<2e−16

IHD

0.8

0.7–1.0

0.01

Age at recruitment (per year)

1.1

1.1–1.1

<2e−16

Female sex

1.1

1.0–1.3

0.04

  1. Adjusted for dyslipidaemia, obesity, hypertension, CKD, PVD, diabetes, IHD, as well as age at enrolment, gender, and two principal components.
  2. CKD chronic kidney disease, IHD ischemic heart disease, PVD peripheral vascular disease.
  3. The exposure of interest for our analysis is shown in bold.
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