Table 1 Number of patients according to the uracil plasma concentration ([U]) and the dihydrouracil/uracil ([UH2]/[U]) plasma ratio.

From: Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity

Phenotype

[U] < 16 ng/mL

[U] ≥ 16 ng/mL

[UH2]/[U] > 10

2344

48

[UH2]/[U] ≤ 10

466

114

Back to article page