Fig. 2: Design and behavioral outcome measures from the NPU sessions | Translational Psychiatry

Fig. 2: Design and behavioral outcome measures from the NPU sessions

From: The relationship between dlPFC activity during unpredictable threat and CO2-induced panic symptoms

Fig. 2

a Schematic demonstrating design of the NPU paradigm. Colored lines indicate blocks of neutral, predictable, and unpredictable threat. Geometric shapes indicate visual cues presented during blocks. Lightning bolts represent timing of shock delivery. b Average anxiety ratings during the fMRI session for the neutral (N), predictable (P), and unpredictable (U) blocks when the cue was present (Cue) or absent (ITI) from the screen. c Startle magnitude (t-scores) during the laboratory session for the neutral (N), predictable (P), and unpredictable (U) blocks when the cue was present (Cue) or absent (ITI) from the screen. d Average anxiety ratings during the laboratory session for the neutral (N), predictable (P), and unpredictable (U) blocks when the cue was present (Cue) or absent (ITI) from the screen. Bars represent the mean ± SEM

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