Table 2 Results of logistic regression models with CRHR1 TAT haplotype count predicting symptom endorsement (binarized), controlling for participant age, sex, and diagnostic group (major depressive disorder with vs. without psychotic features)

From: Corticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression

Symptom

N

Percent endorsed (%)

Step 1: age, sex, and diagnostic group

Step 2: TAT haplotype count

Depressed mood

406

90.4

χ2(3) = 1.88, p = .60

χ2(1) = 6.38, p = .012

Loss of interest

406

94.1

χ2(3) = 0.71, p = .87

χ2(1) = 3.78, p = .052

Change in appetite

403

55.1

χ2(3) = 3.04, p = .39

χ2(1) = 1.12, p = .29

Change in sleep

401

75.1

χ2(3) = 5.69, p = .13

χ2(1) = 0.05, p = .82

Psychomotor agitation/retardation

402

46.8

χ2(3) = 19.48, p < .001

χ2(1) = 3.59, p = .058

(Group: p < .001)

Loss of energy

406

89.4

χ2(3) = 0.83, p = .84

χ2(1) = 0.06, p = .80

Feelings of guilt/worthlessness

402

80.3

χ2(3) = 2.04, p = .56

χ2(1) < 0.001, p = .99

Difficulty concentrating/ indecisiveness

404

86.1

χ2(3) = 5.74, p = .13

χ2(1) = 7.02, p = .008

Suicidality

405

36.0

χ2(3) = 15.36, p = .002

χ2(1) = 1.27, p = .26

(Group: p = .002)