Table 2 Results of logistic regression models with CRHR1 TAT haplotype count predicting symptom endorsement (binarized), controlling for participant age, sex, and diagnostic group (major depressive disorder with vs. without psychotic features)
From: Corticotropin-releasing factor 1 receptor haplotype and cognitive features of major depression
Symptom | N | Percent endorsed (%) | Step 1: age, sex, and diagnostic group | Step 2: TAT haplotype count |
|---|---|---|---|---|
Depressed mood | 406 | 90.4 | Ļ2(3)ā=ā1.88, pā=ā.60 | Ļ2(1)ā=ā6.38, pā=ā.012 |
Loss of interest | 406 | 94.1 | Ļ2(3)ā=ā0.71, pā=ā.87 | Ļ2(1)ā=ā3.78, pā=ā.052 |
Change in appetite | 403 | 55.1 | Ļ2(3)ā=ā3.04, pā=ā.39 | Ļ2(1)ā=ā1.12, pā=ā.29 |
Change in sleep | 401 | 75.1 | Ļ2(3)ā=ā5.69, pā=ā.13 | Ļ2(1)ā=ā0.05, pā=ā.82 |
Psychomotor agitation/retardation | 402 | 46.8 | Ļ2(3)ā=ā19.48, pā<ā.001 | Ļ2(1)ā=ā3.59, pā=ā.058 |
(Group: pā<ā.001) | ||||
Loss of energy | 406 | 89.4 | Ļ2(3)ā=ā0.83, pā=ā.84 | Ļ2(1)ā=ā0.06, pā=ā.80 |
Feelings of guilt/worthlessness | 402 | 80.3 | Ļ2(3)ā=ā2.04, pā=ā.56 | Ļ2(1)ā<ā0.001, pā=ā.99 |
Difficulty concentrating/ indecisiveness | 404 | 86.1 | Ļ2(3)ā=ā5.74, pā=ā.13 | Ļ2(1)ā=ā7.02, pā=ā.008 |
Suicidality | 405 | 36.0 | Ļ2(3)ā=ā15.36, pā=ā.002 | Ļ2(1)ā=ā1.27, pā=ā.26 |
(Group: pā=ā.002) |