Table 3 fMRI Activations from FSL randomise whole brain analysis

From: Brain responses to different types of salience in antipsychotic naïve first episode psychosis: An fMRI study

Anatomical structure

Hemisphere

Cluster size (voxel)

P value (TFCE)

t value

Peak MNI-coordinates

X

y

z

Novel–neutral oddball (novelty)

Cerebellum CrusI

L

221

0.041

4.27

−24

−90

−20

Occipital pole, lingual gyrus

L/R

69

0.048

2.73

4

−94

−4

Occipital pole and cortex

L

23

0.049

3.6

−26

−96

−4

Cerebellum CrusI,II

R

19

0.049

3.85

46

−50

−38

Cerebellum CrusI

L

10

0.048

4.81

−50

−68

−32

Cerebellum CrusI

R

10

0.049

4.07

52

−60

−28

Occipital pole and cortex

L

2

0.05

3.77

−8

−96

−6

Occipital cortex, inferior

L

1

0.05

3.81

−48

−82

4

Emotional–neutral oddball (negative emotional salience)

Lingual gyrus, intracalcarine cortex

R

11327

0.02

3.82

6

−86

−2

Parahippocampus, putamen, nucleus accumbens

L

321

0.041

4.01

−10

2

−20

Occipital cortex, inferior

R

73

0.045

3.39

44

−72

10

Amygdala

L

15

0.046

3.5

−26

−2

−12

Cerebellum CrusI and occipital cortex inferior

L

14

0.048

2.95

−46

−76

−26

Cerebellum lobe X and VIIIb

R

11

0.048

3.14

16

−40

−46

SN/VTA

L

10

0.048

2.51

−12

−16

−6

Frontal operculum cortex

L

9

0.047

2.04

−40

16

4

ACC

R/L

9

0.048

3.19

2

16

18

Parahippocampal gyrus

L

4

0.047

3.43

−14

−14

−24

ACC

L

1

0.05

2.72

−8

6

36

Target–neutral oddball (targetness)

n.s.

Neutral–Standard oddball (rareness)

n.s.

  1. Summary of fMRI results for significant clusters at the whole-brain level, using FSL randomise, variance smoothing: 3 mm, 5000 permutations, and threshold free cluster enhancement (TFCE). Bold values indicate significant differences. n.s. not significant