Fig. 3: Potential mechanisms of MTHFR in psychiatric diseases. | Translational Psychiatry

Fig. 3: Potential mechanisms of MTHFR in psychiatric diseases.

From: Methylenetetrahydrofolate reductase and psychiatric diseases

Fig. 3

Methyl group supply in one-carbon metabolism is affected by MTHFR enzyme catalytic process. MTHFR polymorphism affects downstream methylation of schizophrenia-related proteins. DA, glutamate and so on. BH4, tetrahydrobiopterin; DA, dopamine; NE, norepinephrine; 5-HT, 5-hydroxytryptamine

Back to article page