Table 1 PERMANOVA ranking the association between the altered fecal metabolites and behavior indices/neurotransmitters in the hippocampus

From: Altered gut metabolome contributes to depression-like behaviors in rats exposed to chronic unpredictable mild stress

Phenotype

Degree of freedom

R2

P value

Adjusted P value

Body weight

1

0.06270267

1.10E-03

2.38E-03

Sucrose preference rate

1

0.00683232

8.00E-03

1.39E-02

Grooming time

1

0.01321207

4.08E-02

6.63E-02

Immobility time

1

0.01229415

6.55E-02

1.00E-01

Rearing counts

1

0.06455333

1.10E-03

2.38E-03

Crossing counts

1

0.01299891

3.17E-01

4.58E-01

3-MT

1

0.0517155

1.10E-03

2.38E-03

NE

1

0.03423785

1.10E-03

2.38E-03

5-HT

1

0.03661607

1.10E-03

2.38E-03

DOPAC

1

0.02254633

7.50E-03

1.39E-02

HVA

1

0.06469889

1.10E-03

2.38E-03

KYN

1

0.05594343

1.10E-03

2.38E-03

TRP

1

0.04790959

1.10E-03

2.38E-03

3-HK

1

0.05785465

1.10E-03

2.38E-03

GABA

1

0.02100625

1.30E-03

2.60E-03

5-HIAA

1

0.03044673

1.10E-03

2.38E-03

3-HIAA

1

0.05556307

1.10E-03

2.38E-03

DA

1

0.0444571

1.10E-03

2.38E-03

  1. PERMANOVA permutational multivariate analysis of variance