Fig. 1: Schematic representation of the clinical staging model (7,41).
From: Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging

Stage I: early or late prodromal patients with mild or sub-threshold symptoms; Stage II: first-episode of psychosis (i.e., ‘discrete disorder’); Stage IIIa: incomplete remission; Stage IIIb: one relapse; Stage IIIc: multiple relapses; Stage IV: chronic outcome with severe, persistent illness. This study included patients classified in stages II, IIIa, IIIb or IIIc