Fig. 1: Ancestry analysis of DNA samples that passed quality controls.

a Distribution of genetic ancestry in Alzheimer’s disease (AD) cases and controls. Bar-plots represent each participant on the x-axis, and his percent of European (CEU), African (AFR), and Native American (NAM) ancestry on the y-axis. b Ancestry of rare variant carriers. Box-plots show ancestry composition in percent of people carrying TREM2 p.R47H (n = 3), TREM2 p.R62H (n = 16), PLCG2 p.P522R (n = 6), and ABI3 p.S209F (n = 11) mutations