Table 1 Demographic characteristics of study participants

From: Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging

 

CU/A− (n = 997)

CU/A+ (n = 446)

MCI/A− (n = 78)

MCI/A+ (n = 106)

Total

(n = 1627)

p

Male sex, N (%)

539 (54.1)

232 (52.0)

59 (75.6)

54 (50.9)

884 (54.3)

0.001 a

Age, years

68.7 (61.3, 75.8)

77.2 (71.5, 82.1)

76.7 (69.3, 82.8)

81.3 (75.8, 86.0)

72.7 (64.5, 79.3)

< 0.001 b

Age, N (%); years

     

< 0.001 a

50–69

545 (54.7)

89 (20.0)

20 (25.6)

6 (5.7)

660 (40.6)

 

70–95

452 (45.3)

357 (80.0)

58 (74.4)

100 (94.3)

967 (59.4)

 

Education, years

15.0 (13.0, 16.0)

14.0 (12.0, 16.0)

12.0 (12.0, 16.0)

13.0 (12.0, 16.0)

14.0 (12.0, 16.0)

< 0.001 b

 > 12 years, N (%)

758 (76.0)

316 (70.9)

38 (48.7)

58 (54.7)

1170 (71.9)

< 0.001 a

APOE ε4 carrier, N (%)

205 (21.0){19}

183 (41.5){5}

13 (17.1){2}

53 (50.5){1}

454 (28.4){27}

< 0.001 a

  1. Data presented are median (interquartile range) unless otherwise noted. Significant p values appear bold
  2. CU cognitively unimpaired, MCI mild cognitive impairment, A− normal PiB-PET, A+ abnormal PiB-PET, APOE ε4 Apolipoprotein ε4, {N} number of missing data
  3. aChi-Square test
  4. bKruskal–Wallis test