Fig. 1: CaMKII results in PANDAS/PANS patients by group.

“Original Pediatric Controls” and “Original Pediatric Patients” are the populations originally used to define the threshold of positivity (130) for the CaMKII assay⁶ (Kirvan, C.A., et al., 2006). “All Patients, submitted manuscript” are the values for the CaMKII assay for all patients in a manuscript now under review. “Hesselmark & Bejerot” are all patients as described in ref. ³. Performance metrics can vary in different studies based on the diseased population selected, the inclusion and exclusion criteria for the control population, the impact of interfering substances, and the specimen handling methods in ref. ⁴