Table 3 Heritability of QBS (quantitative bipolarity scale) score

From: Clinical and genetic validity of quantitative bipolarity

 

Whole sample (n = 310)

Whole sample without bipolar (n = 190)

Non-psychiatric control subjects (n = 200)

Unadjusted

 h2

0.46(0.15)

0.55(0.15)

0.59(0.18)

 p

4 × 10−4

4 × 10−5

2 × 10−4

 Age and sex effect (R2)

0.01

0.03

0.05

Adjusted

 h2

0.38(0.17)

0.50(0.17)

0.59(0.18)

 p(h2)

0.008

0.002

2 × 10−4

 Household

0.12(0.09)

0.05(0.08)

0

 p(Household)

0.07

0.25

–

 Age and sex effect (R2)

0.01

0.03

0.05

  1. Additive heritability estimates [h2(SE)] are shown with and without adjustment for shared environment. Household is the proportion of the phenotypic variance attributed to shared environment (household effects). Both models included age and sex as covariates. R2 is the phenotypic variance explained by the covariates age and sex (none was significant)
Back to article page