Table 1 Participant demographic and clinical characteristics.

From: Applying dimensional psychopathology: transdiagnostic associations among regional homogeneity, leptin and depressive symptoms

Characteristic

Group; mean ± SD or no. (%)

Statistics

P value

 

Control (n = 325)

MPDs (n = 403)

  

Demographic characteristics

 Age, years

29.24 (9.94)

28.47 (8.88)

1.091

0.27

 Gender (male/female)

132/193

143/260

2.015

0.156

 Right handedness

303 (93%)

360 (89%)

0.796

0.672

 Weighta

62.41 (14.39)

62.90 (12.93)

−0.479

0.632

 BMI (kg/m2)a

23.76 (26.60)

22.58 (3.90)

0.857

0.392

 Smoking

37/188 (20%)

49/206 (24%)

0.971

0.324

Clinical characteristics

 First episode, yes

–

262 (65%)

–

–

 Medication, yes

–

259 (64%)

–

–

 Antidepressant

–

125 (31%)

  

 Mood stabiliser

–

70 (17%)

–

–

 Antipsychotic

–

124 (31%)

–

–

 Duration, months

–

32.98 (49.21)

–

–

 HAMDb

1.27 (2.16)

13.79 (10.57)

−20.262

<0.001

 YMRSc

0.25 (0.93)

2.97 (6.40)

−7.255

<0.001

 BPRSd

18.42 (1.94)

28.90 (10.08)

−15.779

<0.001

 Leptin (pg/ml)e

5463.13 (4055.93)

9510.14 (9539.14)

−4.011

<0.001

 Leptin (log)e

3.57 (0.44)

3.78 (0.46)

−3.104

0.002

  1. BMI body mass index, BPRS Brief Psychiatric Rating Scale, HAMD Hamilton Depression Scale, YMRS Young Mania Rating Scale.
  2. aControl, n = 314; patients with major psychiatric disorders, n = 385.
  3. bControl, n = 303; patients with major psychiatric disorders, n = 374.
  4. cControl, n = 298; patients with major psychiatric disorders, n = 337.
  5. dControl, n = 237; patients with major psychiatric disorders, n = 303.
  6. eControl, n = 83; patients with major psychiatric disorders, n = 111.
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