Fig. 1: Flowchart of analyses. | Translational Psychiatry

Fig. 1: Flowchart of analyses.

From: Polygenic evidence and overlapped brain functional connectivities for the association between chronic pain and sleep disturbance

Fig. 1

The analyses that were performed in this study included (1) phenotypic correlation, (2) genetic correlation using LD score regression and polygenic score (PGS) association analysis, (3) shared brain functional connectivity (FC) using network-based statistics method by analyzing rfMRI data, (4) association of the PGS with shared brain functional connectivity, and (5) causal relationship inference using Mendelian randomization (MR). HCP (Human Connectome Project) is the data source. N is the sample size for the analysis.

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