Fig. 5: Domain importance in fluid IQ (FIQ) prediction segregated by sex and age.

High versus low FIQ was distinguished based on domains quantified in the Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS). Each plot shows identical analyses on a stratified subset of the patient pool. From upper left to lower right, we selected the adult or teenager male patients, and the adult or teenager female patients. The purple circles show the estimated contribution (y axis) of each particular questionnaire domain (x axis) to distinguishing participants with high versus low FIQ using logistic regression in each specific subgroup. Each green bar indicates the bootstrapped 90% confidence interval at the population level. In teenager males, the repetitive behavior of the ADI-R, the social, and repetitive behavior domains of the ADOS were contributing to having a low FIQ, while the communication domain of the ADOS helped detecting high FIQ. In adult females, the communication domain of the ADI-R and the social domain of the ADOS contributed to detecting a low FIQ, while the repetitive behavior domain of the ADI-R contributed to detecting a high FIQ. In teenager females, the communication and repetitive behavior domains of the ADI-R, as well as the communication domain of the ADOS, were highly associated with detecting high FIQ. Interestingly, the domains of the ADI-R and ADOS were not informative of the patients’ level of FIQ in adult males.