Fig. 2: Gene regulatory network disturbed by the DNMs implicating the enhancers identified by DNM burden test. | Translational Psychiatry

Fig. 2: Gene regulatory network disturbed by the DNMs implicating the enhancers identified by DNM burden test.

From: Retracted: Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts

Fig. 2

Light green arrow nodes are the transcription factors. The yellow round nodes are the enhancers perturbed by the DNMs. The Orange round nodes are the genes. The edge between transcription factor and enhancer represent the transcription factor can bind to the enhancer without the perturbation of DNM. The edge between enhancer and gene represents the enhancer can enhance the expression of the gene without the perturbation of DNM. Red labeled genes were those identified by DNM burden test.

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