Table 2 A table with the four CBCL scales significantly associated with WGCNA modules, and the top 5 ranked genes associated with each scale. Genes are ordered from smallest to largest p-value.

From: Gene co-expression networks in peripheral blood capture dimensional measures of emotional and behavioral problems from the Child Behavior Checklist (CBCL)

CBCL scale

Module

Gene symbol

Beta

SE

P-value

FDRp

Aggression

ME7

SLC9B2

0.011

0.002

3.17 × 10−5

0.025

 

ME7

KIAA0101

0.020

0.005

3.17 × 10−4

0.071

 

ME7

NDUFA4

0.013

0.004

3.47 × 10−4

0.071

 

ME7

S100PBP

0.014

0.004

3.70 × 10−4

0.071

 

ME7

NNT

0.016

0.004

4.86 × 10−4

0.071

Attention problems

ME8

PILRB

−0.042

0.008

1.00 × 10−6

4.25 × 10−4

 

ME8

RP11-434B12.1

−0.015

0.003

1.91 × 10−6

4.25 × 10−4

 

ME16

RNU6-4P

0.015

0.003

1.94 × 10−6

4.25 × 10−4

 

ME27

RPUSD2

−0.036

0.007

1.99 × 10−6

4.25 × 10−4

 

ME8

RP11-219E7.1

−0.033

0.006

2.14 × 10−6

4.25 × 10−4

Social problems

ME8

RP11-253E3.1

−0.027

0.006

1.73 × 10−5

9.61 × 10−3

 

ME8

FAHD2CP

−0.034

0.008

1.95 × 10−5

9.61 × 10−3

 

ME8

IGKV1-39

−0.022

0.005

2.66 × 10−5

9.61 × 10−3

 

ME8

RP3-423B22.5

−0.021

0.005

2.73 × 10−5

9.61 × 10−3

 

ME16

RNU6-4P

0.015

0.003

4.11 × 10−5

0.01

Thought problems

ME7

ADD1

0.015

0.005

1.49 × 10−3

0.46

 

ME7

KIAA0101

0.018

0.006

2.32 × 10−3

0.46

 

ME29

EOGT

−0.015

0.005

2.87 × 10−3

0.46

 

ME21

ANKRD17

0.011

0.004

3.58 × 10−3

0.46

 

ME21

DIABLO

0.011

0.004

3.78 × 10−3

0.46

  1. ME module eigengene, SE standard error, FDRp false discovery rate adjusted p-value.