Fig. 2: Post-retrieval losartan does not alter recall of a conditioned cardiovascular threat responses.

a Schematic of the conditioning, retrieval, and testing protocol used in the radio telemetry experiments (A¹). b Average MAP during 5 min baseline (Pre-CS) and throughout 4 CS presentations during the 24 h memory test (LTM-1d). c Change in MAP during each 30 s CS relative to the Pre-CS period during the LTM-1d test. d Average HR during 5 min baseline (Pre-CS) and throughout 4 CS presentations during the LTM-1d test. e Change in HR during each 30 s CS relative to the Pre-CS period during the LTM-1d test. f Average MAP during 5 min baseline (Pre-CS) and throughout 4 CS presentations during the 1wk long-term memory (LTM-7d) test. g Change in MAP during each 30 s CS relative to the Pre-CS period during the LTM-7d test. h Average HR during 5 min baseline (Pre-CS) and throughout 4 CS presentations during the LTM-7d test. i Change in HR during each 30 s CS relative to the Pre-CS period during the LTM-7d test. ((n = 6 losartan n = 4 saline group, *Pre vs. CS, Bonferroni post hoc, p < 0.05). (A¹) Separate groups of mice were utilized for telemetry studies.