Table 3 Results of statistical models with a significant overall effect of group (NSSI+, NSSI−, CTL) on network coherence with planned linear contrast tests (NSSI+ versus NSSI− and NSSI+ versus CTL).

From: Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression

Model

Statistic

p (corrected)

p (uncorrected or posthoc)

B±SE

Δ R2

DMN-A Coherence

Group

F(2,63) = 6.835

0.007

0.002**

 

0.178

NSSI+ versus NSSI−

t(63) = −2.223

 

0.030*

−0.348 ± 0.157

 

NSSI+ versus CTL

t(63) = −3.568

 

0.0007***

−0.622 ± 0.174

 

DMN-P Coherence

Group

F(2,63) = 5.333

0.016

0.007**

 

0.145

NSSI+ versus NSSI−

t(63) = −1.052

 

0.297

−0.236 ± 0.225

 

NSSI+ versus CTL

t(63) = −3.261

 

0.002**

−0.814 ± 0.250

 

NSSI− versus CTL

t(63) = −2.165

 

0.034*

−0.578 ± 0.267

 

DMN-V Coherence

Group

F(2,63) = 4.102

0.037

0.021*

 

0.115

NSSI+ versus NSSI−

t(63) = −2.456

 

0.017*

−0.459 ± 0.187

 

NSSI+ versus CTL

t(63) = −2.279

 

0.026*

−0.473 ± 0.207

 

SN-Ins Coherence

Group

F(2,63) = 8.833

0.003

0.0004***

 

0.219

NSSI+ versus NSSI−

t(63) = −3.329

 

0.001**

−0.731 ± 0.220

 

NSSI+ versus CTL

t(63) = −3.618

 

0.0006***

−0.883 ± 0.244

 
  1. Posthoc linear contrast tests (NSSI- versus CTL) with significant results are also reported. All results shown include age, sex, motion, and medication use as covariates (see Table S2 for more details). See Fig. 3 for more details. FDR-corrected p-values are reported for the main effect of group only.
  2. NSSI non-suicidal self-injury, CTL healthy control, DMN-A Anterior Default Mode Network, DMN-P Posterior Default Mode Network, DMN-V Ventral Default Mode Network, SN-Ins Salience Network-Insula.
  3. *p < 0.05, **p < 0.01, ***p < 0.001.