Table 1 Cohort characteristics.

From: Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer’s disease

 

Aβ−

Aβ+

p

Sex (male/female)

18/45

13/20

0.281

Age (years, mean ± SD)

77.41 ± 5.45

79.64 ± 5.20

0.057

BMI (mean ± SD)

27.28 ± 4.51

27.36 ± 3.79

0.927

APOE ε4 carriers (N (%))

5 (7.94)

14 (42.42)

<0.0001

MMSE (mean ± SD)

28.52 ± 1.16

28.82 ± 1.07

0.230

Subjective memory complainers (N (%))

49 (77.8)

25 (75.76)

0.823

FBB-PET SUVR (mean ± SD)

1.16 ± 0.09

1.71 ± 0.26

—

  1. Baseline characteristics including sex, age, body mass index (BMI), APOE ε4 status, Mini-mental State Examination (MMSE) scores, subjective memory complainer status (assessed by the Memory Assessment Clinic-Questionnaire (MAC-Q) score), and brain Aβ load represented by the standard uptake value ratio (SUVR) of ligand 18F-florbetaben (FBB) in the neocortical region normalised with that in the cerebellum, have been compared between Aβ− (SUVR < 1.35, n = 63) and Aβ+ (SUVR ≥ 1.35, n = 33) study participants. Chi-square tests or linear models were employed as appropriate.
Back to article page