Table 1 Demographic overview of cohorts.

From: Combined effects of genotype and childhood adversity shape variability of DNA methylation across age

Cohort

Na

Mean age (SD)

Sex (male)

Ethnicity

Assessment of CA

CA Na (%)

Tissue

Methylation array

GRADY

309

42.08 (12.92)

25.56%

African American

Self-report

148 (47.90%)

Whole blood

450K

PReDICT

363

39.83 (11.50)

39.67%

Mixed

Self-report

164 (45.18%)

Whole blood

450K

U19

78

39.27 (12.10)

0.00%

Mixed

Self-report

66 (84.62%)

Whole blood

450K

BerlinLCS

173

4.23 (0.79)

52.60%

Caucasian

Documented

86 (49.71%)

Saliva

EPIC

HBCS

151

63.5 (2.8)

100%

Finnish

Documented

77 (51.00%)

Whole blood

450K

  1. In GRADY, PReDICT, and U19 CA refers to moderate-to-severe ranges of CTQ scores for either sexual, physical, or emotional abuse (GRADY n = 77, PReDICT n = 79, U19 n = 14) or to moderate-to-severe scores in at least two abuse groups (GRADY n = 71, PReDICT n = 85, U19 n = 52), in BerlinLCS CA refers to maltreatment and in HBCS to evacuation and separation from parents in World War II.
  2. SD standard deviation, CA childhood adversity.
  3. aN = sample size.
Back to article page