Table 1 Sample characteristics.

From: Probing the clinical and brain structural boundaries of bipolar and major depressive disorder

Variable

Patients with BD

N = 90

Patients with MDD

N = 189

Healthy Individuals

N = 162

Age (years)

26.44 (5.87)a,b

27.84 (6.19)

27.77 (5.21)

Sex (Male/Female)

36/54

71/118

67/95

Education (years)

14.78 (2.43)a

14.98 (2.83)

15.51 (2.75)

Marital status

Single

57 (69.51)a,b

105 (58.01)a

102 (62.96)

Married/cohabitation

18 (21.95)

67 (37.02)

60 (37.04)

Divorce/separation

7 (8.54)

9 (4.97)

0 (0.00)

Employment status

Unemployment

13 (16.46)a,b

52 (32.30)a

9 (5.56)

Part-time employment

3 (3.80)

8 (4.97)

2 (1.23)

Full-time employment

38 (48.10)

73 (45.34)

91 (56.17)

Students

25 (31.65)

28 (17.39)

60 (37.04)

BMI

22.67 (3.89)

21.76 (3.62)

22.42 (2.92)

HAMD total score

21.82 (4.48)a

21.20 (4.11)a

1.58 (1.76)

YMRS total score

2.46 (3.17)a,b

1.11 (1.51)

1.00 (1.92)

HAMA total score

17.70 (7.04)

17.05 (6.44)

n/a

Age of onset (years)

20.16 (5.52)b

25.13 (7.17)

n/a

Number of episodes

5.37 (6.31)b

1.65 (1.08)

n/a

Illness duration (months)

73.48 (57.31)b

45.00 (55.30)

n/a

GAF score

51.62 (6.39)b

54.67 (6.50)

n/a

SDS score

  

n/a

SDS-work/study

6.68 (2.86)

7.37 (8.96)

 

SDS-social life

6.48 (2.70)

6.35 (2.53)

 

SDS-family life

6.27 (2.72)

5.73 (2.81)

 

Positive family history of psychiatric disorders

16 (21.05)

26 (15.95)

0 (0.00)

Never medicated

52 (67.53)

114 (70.80)

n/a

  1. Continuous variables are shown as mean (standard deviation); Employment status, marital status, medication status, and family history are shown as number (percentage).
  2. BD bipolar disorder, MDD major depressive disorder, BMI body mass index, HAMD Hamilton depression scale, YMRS Young Mania rating scale, HAMA Hamilton anxiety scale, GAF global assessment of function, SDS Sheehan disability scale, n/a not available or not applicable.
  3. aDifferences between each diagnostic group and healthy individuals at PFDR < 0.05.
  4. bDifferences between the two diagnostic groups at PFDR < 0.05; further details in the Supplemental Material.