Fig. 2: Removal of S6K1 spares spatial navigation but impairs contextual fear memory. | Translational Psychiatry

Fig. 2: Removal of S6K1 spares spatial navigation but impairs contextual fear memory.

From: Inhibition of mTOR signaling by genetic removal of p70 S6 kinase 1 increases anxiety-like behavior in mice

Fig. 2

a Latency to find the platform during reference memory testing (b) latency to find the platform location from constant start positions (C1 to C5) and a novel start position (N). c Freezing behavior (% total time) in response to a shock-associated context. d Threshold to elicit a flinch, jump or vocalize behavior in response to shocks of ascending intensity. e Latency to paw licking in response to ascending temperatures in the hot plate test. Data are mean ± SEM. n = 11 mice per genotype. *p < 0.05 compared to WT.

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