Fig. 3: Removal of S6K1 increases anxiety-related behaviors. | Translational Psychiatry

Fig. 3: Removal of S6K1 increases anxiety-related behaviors.

From: Inhibition of mTOR signaling by genetic removal of p70 S6 kinase 1 increases anxiety-like behavior in mice

Fig. 3

Anxiety-like responses were measured in the elevated plus maze (a, b, e, f), in the open-field (c, g) and in the light/dark emergence task (d, h) under baseline conditions (top) or after cage enrichment with a running wheel (bottom). Data are mean ± SEM, n = 11 per genotype and per test except for the elevated plus maze under baseline conditions where one S6K1-KO mouse was removed as it fell from the maze. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to the WT.

Back to article page