Table 1 Demographic information and clinical characteristics of the study population.

From: Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios

 

Control

Bumetanide

Degree of freedom

Statistic

p value

Num.

Min

Max

Mean

SD

Num.

Min

Max

Mean

SD

Sex (F, M)

12, 29

6, 36

1.00

2.7422

0.098

Age

41

3

6.69

3.97

1.01

42

3.01

6.04

4.19

0.95

80.42

−0.9949

0.3228

IQ

41

35

97

62.28

16.51

42

27.4

90

60.84

13.75

77.74

0.4320

0.6669

ADIR

TotalA

41

12

30

19.39

4.85

42

11

29

20.40

4.20

79.80

−1.0184

0.3116

TotalBv

34

6

21

13.65

4.39

24

8

23

13.96

3.85

53.30

−0.2860

0.7760

TotalBnv

7

7

14

11.29

2.29

18

5

14

11.11

2.91

13.96

0.1582

0.8766

TotalC

41

3

11

6.07

2.18

42

3

10

5.98

1.99

79.94

0.2111

0.8333

TotalD

41

1

6

3.83

1.69

42

1

6

4.07

1.35

76.50

0.7209

0.4731

ADOS

TotalA

41

3

10

6.34

1.59

42

3

8

6.21

1.34

77.96

0.3941

0.6946

TotalB

41

7

113

13.37

16.09

42

5

14

10.52

2.35

41.67

1.1196

0.2693

TotalC

41

11

22

17.27

3.38

42

9

22

16.74

3.44

81.00

0.7090

0.4804

TotalD

41

0

6

2.85

1.54

42

0

6

2.64

1.34

78.89

0.6641

0.5086

TotalE

41

0

4

1.95

1.05

42

0

5

2.26

1.21

79.86

−1.2510

0.2146

CARS

Total score

41

30

46.5

38.15

4.04

42

31.5

43.5

37.40

3.20

76.12

0.9267

0.3570

Num.item ≥ 3

41

1

15

6.32

3.57

42

1

12

5.93

3.03

78.31

0.5341

0.5948

  1. Numbers of subjects with a particular characteristic are listed as integers, and quantitative measurements are presented as mean values ± standard deviations. Inter-group differences are evaluated with Welch’s t test for continuous variables and Pearson’s chi-squared test for categorical variables
  2. IQ intelligence quotient, ADIR The Autism Diagnostic Interview-Revised, TotalBv Total B score of ADIR for verbal subjects, TotalBnv Total B score for nonverbal subjects, CARS Childhood Autism Rating Scale, Num. item ≥ 3 number of items assigned a score ≥ 3
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