Fig. 1: Association of genome-wide genetic variants in clozapine-induced myocarditis cases compared with clozapine-tolerant controls.
From: Genetic associations with clozapine-induced myocarditis in patients with schizophrenia
The first four principal components and valproate use were included as covariates. a Manhattan plot showing individual −log10 P values plotted against their genomic position by chromosome. The red line represents the threshold of genome-wide significance (P = 5 × 10−8). The blue line marks the threshold for suggestive association (P = 1 × 10−5). Blue arrows indicate SNPs with P < 1 × 10−6. b Quantile−quantile (Q−Q) plot of data shown in Manhattan plot.
