Table 3 Correlation analyses between THC and endocrine markers AUCs.

From: Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study

 

Total ghrelin AUC

Acyl-ghrelin AUC

Leptin AUC

GLP-1 AUC

Insulin AUC

THC AUC, oral cannabis session

r = 0.02, p = 0.91

r = 0.08, p = 0.71

r = −0.16, p = 0.51

r = −0.01, p = 0.96

r = −0.09, p = 0.69

THC AUC, smoked cannabis session

r = 0.16, p = 0.52

r = 0.08, p = 0.73

r = 0.27, p = 0.28

r = −0.07, p = 0.77

r = −0.17, p = 0.47

THC AUC, vaporized cannabis session

r = 0.56, p = 0.01

r = 0.40, p = 0.07

r = 0.06, p = 0.80

r = 0.13, p = 0.57

r = −0.20, p = 0.39

THC AUC, three sessions combined

r = 0.12, p = 0.35

r = 0.14, p = 0.27

r = 0.11, p = 0.39

r = 0.02, p = 0.85

r = −0.009, p = 0.94

  1. AUC area under the curve, GLP-1 glucagon-like peptide 1, THC tetrahydrocannabinol.
  2. THC AUC was calculated using measurements at T0, T2, T3, and T4. Hormones AUC was calculated using measurements at T1, T2, T3, and T4. See Fig. 1.
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