Table 2 DGE model results ordered by FDR.

From: Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder

(a) Standard model

(b) xCell enrichment

Name

LogFC

P Value

FDR

LogFC

P Value

FDR

HMGB3

−0.306

6.15e-08

8.99e−04

−0.250

2.02e-05

1.54e−01

NMUR1

−0.345

3.30e-06

2.41e−02

−0.224

2.11e-05

1.54e−01

PTPRN2

0.294

6.47e-06

2.84e−02

0.290

3.36e-05

1.63e−01

NKG7

−0.355

8.01e-06

2.84e−02

−0.207

6.71e-04

9.93e−01

PIF1

−0.413

105e-05

2.84e−02

−0.299

7.54e-04

9.93e−01

KLRD1

−0.240

1.23e-05

2.84e−02

−0.145

7.39e-04

9.93e−01

FKBP11

−0.210

1.36e-05

2.84e−02

−0.159

1.31e-03

9.93e−01

GLNY

−0.451

1.75e-05

3.20e−02

−0.302

5.76e-04

9.93e−01

CLIC3

−0.415

2.07e-05

3.36e−02

−0.269

1.69e-03

9.98e−01

MANF

−0.176

2.69e-05

3.93e−02

−0.141

1.36e-03

9.93e−01

  1. (a) Results obtained by the paired design, including technical and demographic covariates (“standard model”).
  2. (b) Results obtained by including in the standard model the cell composition score derived by cell deconvolution analysis with xCell as additional covariate. Only results for FDR < 0.05 from the standard model are shown in the table.
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