Table 3 Differential composition and cell type enrichment by using two different deconvolution approaches.

From: Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder

(a) CIBERSORT differential cell composition

(b) xCell differential cell composition

Cell types

logFC enrich

P Value

FDR

Cell types

logFC enrich

P Value

FDR

NK.cells.resting

−0.0215673

3.66e−04

8.05e−03

NK cells

−0.0030001

7.45e−03

6.81e−02

Neutrophils

0.0340265

1.11e−02

1.22e−01

Tgd cells

−0.0008546

9.08e−03

6.81e−02

B.cells.naïve

0.0084004

4.30e−02

2.68e−01

naïve B cells

0.0038983

3.69e−02

1.39e−01

T.cells.CD8

−0.0134798

5.95e−02

2.68e−01

CD4+ Tem

−0.0029231

3.70e−02

1.39e−01

Macrophages.M0

0.0006095

6.10e−02

2.68e−01

B cells

0.0064601

5.44e−02

1.63e−01

  1. (a) On the left, using CIBERSORT with LM 22 base matrix.
  2. (b) On the right, using xCell algorithm FDR correction with the Benjamini–Hochberg method.