Table 1 Main characteristics of the included studies involving sedentary behavior and the risk of dementia.
Author | Year | Country (state) | Age | Sample size | Cases | Adjustments |
|---|---|---|---|---|---|---|
Deckers K. | 2017 | UK (Europe) | 87.7 ± 2.7 | 323 | 76 | Age, sex and educational level |
Kishimoto H. | 2016 | Japan (Asia) | ≥65 | 803 | 93 | NR |
T. Luck | 2016 | Germany (Europe) | NR | 217,000 | NR | NR |
MacDonald J.P. | 2015 | Canada (America) | ≥50 | 5219 | NR | NR |
T. Luck | 2014 | Germany (Europe) | 81.1 ± 3.5 | 2492 | 278 | Age, gender, level of education, MMSE scores, comorbidity |
Mehlig K. | 2014 | Sweden (Europe) | 38-60 | 1448 | 165 | Baseline covariates age, education, smoking, consumption of alcohol, triglycerides, hypertension, and parental history of diabetes |
Norton S. | 2014 | Sweden (Europe) | 82.1 ± 5 | 180 | 36 | Education, portion of fruits/vegetables in diet, current smoking status, alcohol consumption, body-mass index, and angina pectoris |
de Bruijn R.F. | 2013 | Netherlands (Australia) | 72.7 ± 7.2 | 4406 | 490 | Age, sex, score on MMSE, low educational level, smoking, APOE-e4 carrier status, hypertension, BMI, diabetes, total cholesterol, and HDL-cholesterol |
Verdelho A. | 2012 | Portugal (Europe) | 65-84 | 639 | 34 | Age, educational level, sex, white matter changes severity, and medial temporal atrophy |
Gelber R.P. | 2012 | American | 71–93 | 3468 | 117 | Age, years of education, APOE e4 status, childhood years spent in Japan, occupational status, high cholesterol, and history of hypertension, diabetes, and cardiovascular disease |
Keller L. | 2010 | Sweden (Europe) | NR | 936 | 243 | Age, gender, education and APOE, TT, BMI, diabetes, CVD |
Scarmeas N. | 2009 | American | 77 | 1880 | 282 | Age, sex, ethnicity, education, apolipoprotein E ε4 allele, caloric intake, body-mass index, smoking, depression, leisure activities, comorbidity index, baseline Clinical Dementia Rating score, and time between first dietary and first physical activity assessment |
Kivipelto M. | 2008 | Finland (Europe) | 70.8 ± 3.7 | 1284 | 57 | Age, sex, follow-up time, education, body-mass index, serum cholesterol, systolic blood pressure, myocardial infarction, stroke, diabetes mellitus and ApoE4 carriers status sex, education, follow-up time, locomotor disorders, APOE 4 genotype, midlife body-mass index, systolic blood pressure, cholesterol, and history of myocardial infarction, stroke, diabetes mellitus, smoking status, and alcohol drinking |
Rovio S. | 2007 | Finland (Europe) | 70 | 1158 | 33 | NR |
Rovio S. | 2005 | Finland (Europe) | 70.9 ± 3.9 | 1935 | 76 | Age at re-examination, APOE 4 genotype, midlife body-mass index, systolic blood pressure, cholesterol, and history of myocardial infarction, stroke, diabetes mellitus, smoking status and alcohol drinking |
Anttila T. | 2003 | Finland (Europe) | 74 ± 4 | 1449 | 70 | Age and APOE ε4 carrier status |
Laurin D. | 2001 | Canada | 80 | 4615 | 169 | Age, sex, and educational level |
Yoshitake T. | 1995 | Japan (Asia) | Men: 73 ± 5.6 Women: 74 ± 6.1 | 828 | 50 | Age |
