Fig. 1: Horvath and Hannum epigenetic age acceleration. | Translational Psychiatry

Fig. 1: Horvath and Hannum epigenetic age acceleration.

From: Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder

Fig. 1

a, b Scatterplots show Horvath or Hannum Age vs. chronological age. Pearson’s correlation analysis indicated a significant correlation between DNA methylation age and chronological age in both groups. c–f Violin-plot with dots shows Horvath EAA, IEAA, Hannum EAA, or EEAA. Between-group comparisons were conducted using a Student’s t-test. Compared with controls, Horvath EAA (p = 0.0365) and IEAA (p = 0.0389) were significantly decreased in patients with BD. CTL, control; BD, bipolar disorder; EAA, epigenetic age acceleration; IEAA, intrinsic epigenetic age acceleration; EEAA, extrinsic epigenetic age acceleration.

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