Table 1 Socio-demographics and clinical characteristics between MDD comorbid anxiety symptoms with suicide attempts and without suicide attempts.

From: The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study

Variable

MDD comorbid anxiety symptoms

F/χ2/z

p

With SA (N = 335)

Without SA (N = 1045)

Age

36.15 ± 12.33

34.57 ± 12.50

4.25

0.04

Gender

  

0.70

0.41

 Male, n (%)

109 (32.5%)

366 (35%)

  

 Female, n (%)

226 (67.5%)

679 (65%)

  

Education

  

9.55

0.02

 Junior high school, n (%)

98 (29.3%)

234 (22.4%)

  

 High school, n (%)

135 (40.3%)

467 (44.7%)

  

 University degree, n (%)

79 (23.6%)

292 (27.9%)

  

 Master’s degree, n (%)

23 (6.9%)

52 (5.0%)

  

Marital status

  

0.45

0.50

 Single, n (%)

92 (27.5%)

307 (29.4%)

  

 Married, n (%)

243 (72.5%)

738 (70.6%)

  

Age of onset, years

35.91 ± 12.24

34.38 ± 12.37

4.38

0.04

Illness duration, months

6.98 ± 4.93

6.11 ± 4.59

9.45

0.002

HAMD

32.36 ± 2.81

30.358 ± 2.63

131.18

<0.001

HAMA

23.83 ± 3.34

21.28 ± 2.52

209.28

<0.001

Psychotic positive score

11.62 ± 6.55

8.53 ± 3.78

107.12

<0.001

BMI, kg/m2

24.34 ± 2.32

24.38 ± 1.79

0.17

0.68

Systolic BP, mmHg

124.47 ± 12.05

118.70 ± 10.31

80.73

<0.001

Diastolic BP, mmHg

78.64 ± 7.70

75.64 ± 6.34

47.84

<0.001

TC, mmol/L

5.80 ± 1.11

5.23 ± 1.07

64.91

<0.001

TG, mmol/L

2.31 ± 1.01

2.16 ± 0.97

5.44

0.02a

HDL-C, mmol/L

1.14 ± 0.29

1.24 ± 0.29

28.99

<0.001

LDL-C, mmol/L

3.23 ± 0.91

3.01 ± 0.84

14.67

<0.001

FBG, mmol/L

5.59 ± 0.75

5.37 ± 0.63

24.44

<0.001

TSH, uIU/mL

6.78 ± 2.91

4.81 ± 2.43

143.10

<0.001

FT3, pmol/L

4.92 ± 0.73

4.91 ± 0.71

0.33

0.57

FT4, pmol/L

16.60 ± 3.14

16.72 ± 3.09

0.04

0.84

TgAb, IU/L

151.51 ± 304.32

85.30 ± 244.36

15.21

<0.001

TPOAb, IU/L

151.48 ± 249.59

57.41 ± 134.25

74.74

<0.001

  1. HAMD Hamilton Rating Scale for Depression, HAMA Hamilton Anxiety Rating Scale, BMI body mass index, BP blood pressure, TC total cholesterol, TG triglycerides, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, FBG fasting blood glucose, TSH thyroid stimulating hormone, FT3 free triiodothyronine, FT4 free thyroxine, TgAb antithyroglobulin, TPOAb thyroid peroxidases antibody.
  2. aDid not survive after Bonferroni correction.