Table 5 Comparison of differentially expressed genes at the third trimester of pregnancy associated with PPD with previously reported maternal genes by Gammie et al. 2016.

From: Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape

Symbol

Probe

Chr

P value_EPDSv2

FDR_EPDSv2

P value_diffEPDSv2

FDR_diffEPDSv2

P value_PPD

FDR_PPD

P value_Dep

FDR_Dep

ADCY5

111

3

0.014050053

0.554047576

0.002962235

0.216262025

0.91178575

0.99980319

0.98965523

0.99997367

ASAP2

8853

2

0.23315749

0.999797241

0.832816451

0.999245113

0.4734246

0.99980319

0.73193125

0.99997367

ATP10A

57194

15

0.071056678

0.999797241

0.041084579

0.660254558

0.99541483

0.99980319

0.94005609

0.99997367

BCL2L1

598

20

0.011365889

0.515005387

0.914054201

0.999245113

0.98761521

0.99980319

0.32804887

0.99997367

CADPS

8618

3

0.212269446

0.999797241

0.795011

0.999245113

0.77701682

0.99980319

0.81620633

0.99997367

CCDC85B

11007

11

0.025452704

0.739222531

0.363283011

0.999245113

0.05392936

0.99980319

0.26021851

0.99997367

CD200

4345

3

0.093184684

0.999797241

0.232688233

0.969329781

0.00999878

0.80474158

0.02667391

0.99997367

CNTNAP3

79937

9

0.016675728

0.616660406

0.024084768

0.559265472

0.71961007

0.99980319

0.3454232

0.99997367

DAAM2

23500

6

0.618068822

0.999797241

0.465553179

0.999245113

0.33148853

0.99980319

0.43262365

0.99997367

DDAH2

23564

6

0.121695981

0.999797241

0.633074639

0.999245113

0.10762088

0.99980319

0.34735339

0.99997367

DLC1

10395

8

0.18544046

0.999797241

0.020026641

0.514369946

0.19652235

0.99980319

0.42960279

0.99997367

DSCAM

1826

21

0.002077118

0.191346638

0.675666126

0.999245113

0.62745455

0.99980319

0.97833471

0.99997367

DZIP1

22873

13

0.268435651

0.999797241

0.567421782

0.999245113

0.70184475

0.99980319

0.95756208

0.99997367

ENG

2022

9

0.852264699

0.999797241

0.230231174

0.966439689

0.65484722

0.99980319

0.49902445

0.99997367

FBN1

2200

15

0.030794244

0.826999396

0.9026211

0.999245113

0.88818414

0.99980319

0.89595002

0.99997367

FLT1

2321

13

0.570727567

0.999797241

0.038153876

0.647066685

0.00242766

0.38734395

0.06800417

0.99997367

FRAS1

80144

4

0.008458146

0.439583873

0.39781099

0.999245113

0.95921892

0.99980319

0.93647918

0.99997367

FSTL5

56884

4

8.78E-05

0.023000406

0.050527822

0.708162007

0.00970811

0.8009674

0.03873353

0.99997367

FXYD1

5348

19

0.018867223

0.646818417

0.762825669

0.999245113

0.92048491

0.99980319

0.88225019

0.99997367

GCNT2

2651

6

0.212632395

0.999797241

0.024135941

0.559265472

0.91377176

0.99980319

0.72771845

0.99997367

GLDC

2731

9

0.018982052

0.646818417

0.039814013

0.653570948

0.2049579

0.99980319

0.36900048

0.99997367

GPR27

2850

NA

0.703341699

0.999797241

0.008356958

0.348306075

0.26369055

0.99980319

0.56382651

0.99997367

GPRIN3

285513

4

0.158689278

0.999797241

0.007280647

0.331404856

0.5722268

0.99980319

0.74894925

0.99997367

HIF1A

3091

14

0.083348331

0.999797241

0.805687086

0.999245113

0.00235364

0.38734395

0.05975394

0.99997367

HIST1H1C

3006

6

0.371095763

0.999797241

0.91982595

0.999245113

0.00481477

0.56509769

0.19892836

0.99997367

HIST1H2BK

85236

6

0.418176509

0.999797241

0.449859358

0.999245113

0.0580796

0.99980319

0.33328433

0.99997367

HMGB3

3149

X

0.001054142

0.116964982

0.170650959

0.957043264

0.57580736

0.99980319

0.49913663

0.99997367

HOMER1

9456

5

0.002422146

0.207713945

0.928286192

0.999245113

0.99781621

0.99980319

0.99212125

0.99997367

HPCAL4

51440

1

0.962836118

0.999797241

0.404980957

0.999245113

0.00948858

0.79615389

0.07530006

0.99997367

HSPB1

3315

7

0.774603671

0.999797241

0.008067963

0.341040786

0.02324166

0.99980319

0.24558202

0.99997367

LRRC29

26231

16

0.399050799

0.999797241

0.022297823

0.540070111

0.33786985

0.99980319

0.62596094

0.99997367

MAP3K15

389840

X

0.420717446

0.999797241

0.958895197

0.999245113

0.22671791

0.99980319

0.45515549

0.99997367

MCF2L

23263

13

0.398696592

0.999797241

0.001172201

0.13316409

0.25535639

0.99980319

0.20225951

0.99997367

MERTK

10461

2

0.101097195

0.999797241

0.044390268

0.678278078

0.63289989

0.99980319

0.40555607

0.99997367

NEURL1B

54492

5

0.036201122

0.879054327

0.11249574

0.877771504

0.94603704

0.99980319

0.9241486

0.99997367

NEXN

91624

1

0.388511732

0.999797241

0.021162427

0.524521154

0.3702592

0.99980319

0.6356162

0.99997367

NR1D1

9572

17

0.244295838

0.999797241

0.032187846

0.615427276

0.48714116

0.99980319

0.99394571

0.99997367

NR4A1

3164

12

0.54874689

0.999797241

0.811163817

0.999245113

0.03001189

0.99980319

0.08679762

0.99997367

NSUN3

63899

3

0.586484515

0.999797241

0.459638237

0.999245113

0.08934916

0.99980319

0.08254255

0.99997367

OLIG2

10215

21

0.063562425

0.999797241

0.026373718

0.585711441

0.00299288

0.42688463

0.0149956

0.99997367

PDP1

54704

8

0.885184882

0.999797241

0.669359061

0.999245113

0.64335095

0.99980319

0.58963618

0.99997367

PHLPP2

23035

16

0.755938138

0.999797241

0.596468698

0.999245113

0.03355505

0.99980319

0.09609877

0.99997367

PLCB1

23236

20

0.348381116

0.999797241

0.020000685

0.514369946

0.50119888

0.99980319

0.79923428

0.99997367

PLIN4

729359

19

0.408653941

0.999797241

0.033853456

0.62292633

0.48816799

0.99980319

0.35878095

0.99997367

PLLP

51090

16

0.746268876

0.999797241

0.006307858

0.305379969

0.75307827

0.99980319

0.66400787

0.99997367

PPP1R12B

4660

1

0.04338289

0.947889322

0.039379693

0.652530615

0.28069488

0.99980319

0.38859106

0.99997367

PSD

5662

10

0.923810949

0.999797241

0.042759347

0.672382742

0.6654271

0.99980319

0.45005221

0.99997367

PSPH

5723

7

0.686104071

0.999797241

0.873717886

0.999245113

0.42450925

0.99980319

0.92148676

0.99997367

RAB30

27314

11

0.71805606

0.999797241

0.061149329

0.745952208

0.01561673

0.94562271

0.06022857

0.99997367

RASA3

22821

13

0.772698055

0.999797241

0.011718405

0.413266918

0.68529277

0.99980319

0.88951742

0.99997367

RASGEF1B

153020

4

0.606014303

0.999797241

0.900764539

0.999245113

0.01995988

0.99980319

0.04431899

0.99997367

RFTN1

23180

3

0.509223491

0.999797241

0.001629844

0.158502285

0.566442

0.99980319

0.97046749

0.99997367

SBK1

388228

16

0.814900153

0.999797241

0.032447549

0.615427276

0.94079819

0.99980319

0.76509714

0.99997367

SERINC2

347735

1

0.001346019

0.142800404

0.098238466

0.848244582

0.93519291

0.99980319

0.3510916

0.99997367

SGSM1

129049

22

0.426624611

0.999797241

0.347460956

0.999245113

0.96549994

0.99980319

0.8219647

0.99997367

SLC2A1

6513

1

0.197794608

0.999797241

0.73633701

0.999245113

0.00110525

0.21827851

0.0049442

0.99997367

SLC38A5

92745

X

0.009995578

0.474076994

0.893153414

0.999245113

0.84453604

0.99980319

0.35205746

0.99997367

SLC4A4

8671

4

0.960039114

0.999797241

0.458677999

0.999245113

0.02456949

0.99980319

0.04855063

0.99997367

SLC4A8

9498

12

0.466064002

0.999797241

0.029660741

0.604610542

0.02353749

0.99980319

0.15735593

0.99997367

SMOX

54498

20

0.060547007

0.999797241

0.033388089

0.621163618

0.19395148

0.99980319

0.93632637

0.99997367

SNRK

54861

3

0.221630481

0.999797241

0.052251277

0.711293364

0.00027156

0.07416982

0.01404638

0.99997367

SOCS3

9021

17

0.902530531

0.999797241

0.090285457

0.832799778

0.97152061

0.99980319

0.99901805

0.99997367

SORCS2

57537

4

0.1797705

0.999797241

0.001092399

0.133018019

0.01452102

0.92830067

0.30719731

0.99997367

TMEM165

55858

4

0.990113374

0.999797241

0.323611169

0.999245113

0.69745403

0.99980319

0.67185592

0.99997367

TNFRSF12A

51330

16

0.69170039

0.999797241

0.213123462

0.964674548

0.68818696

0.99980319

0.83076288

0.99997367

TRIM9

114088

14

0.642086487

0.999797241

0.206442423

0.961442886

0.01238762

0.88646873

0.04950842

0.99997367

ZER1

10444

9

0.008606227

0.443784651

0.288011553

0.994394748

0.4064001

0.99980319

0.27713802

0.99997367

ZFP57

346171

6

0.688934236

0.999797241

9.57E-12

3.07E-08

0.00014379

0.04988752

0.0056805

0.99997367

ZNF512B

57473

20

0.188375011

0.999797241

0.005563967

0.293928586

0.93831436

0.99980319

0.56044337

0.99997367

ZXDB

158586

X

0.309677897

0.999797241

0.862922218

0.999245113

0.39484065

0.99980319

0.6766835

0.99997367

  1. EPDS Edinburgh Postnatal Depression Scale symptoms at 2 months postpartum, diffEPDS difference in EPDS symptoms from the third trimester of pregnancy to 2 months postpartum, PPD EPDS symptoms in the PPD group, Dep EPDS symptoms in the depression group, GnRHa_estradiol genes associated with estradiol in the GnRHa study, FDR P values after false discovery rate multiple testing.
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