Table 3 Genes detected in the MAGMA gene analyses.

From: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments

Environment

Gene

Chr

BPSTART

BPSTOP

PGWEIS

PGWAS

Alcohol intake

CLDN4

7

73,213,872

73,247,014

1.16eāˆ’7

0.190

WBSCR27

7

73,248,920

73,256,865

1.44eāˆ’6

0.093

Chronic pain

VPS9D1

16

89,773,542

89,787,394

5.59eāˆ’7

0.532

FANCA

16

89,803,957

89,883,065

1.30eāˆ’6

0.016

Intelligence

EIF5A

12

7,210,318

7,215,774

8.43eāˆ’7

0.116

POLE

12

133,200,348

133,263,951

1.18eāˆ’6

0.080

Family satisf.

CWC27

5

64,064,757

64,314,590

1.22eāˆ’6

0.054

Sexual assault

FHIT

3

59,735,036

61,237,133

1.15eāˆ’6

1eāˆ’4

Social activities

ZSWIM3

20

44,486,256

44,507,761

1.85eāˆ’6

0.097

Y/o schooling

TUSC5

17

1,182,957

1,204,281

2.14eāˆ’6

0.702

  1. Results from MAGMA gene analysis of 19,831 genes, using the GWEIS interaction p-values as input (p < 0.05/19,831 = 2.52eāˆ’6); No gene survived additional Bonferroni correction for the number of environments analysed (p < 2.52eāˆ’6/25 = 1.01eāˆ’7).