Fig. 1: Effects of polygenic risk scores (PRSs) for psychiatric and neurodevelopmental disorders. | Translational Psychiatry

Fig. 1: Effects of polygenic risk scores (PRSs) for psychiatric and neurodevelopmental disorders.

From: Polygenic risk scores for major psychiatric and neurodevelopmental disorders contribute to sleep disturbance in childhood: Adolescent Brain Cognitive Development (ABCD) Study

Fig. 1

Effects of polygenic risk scores (PRSs) for psychiatric and neurodevelopmental disorders (ASD, SCZ, ADHD, MDD, and BIP) at each threshold (PT cutoff) on the risk of sleep disturbance in early adolescence in children of European ancestry. The y-axis represents the adjusted R2, indicating the explanatory power of the model. ASD, autism spectrum disorder; SCZ, schizophrenia; ADHD, attention-deficit/hyperactivity disorder; MDD, major depressive disorder; BIP, bipolar disorder. ***p < 0.001, **p < 0.01, *p < 0.05.

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