Fig. 4: The relationship of serum levels of 5-HI with cortical thickness in patients with schizophrenia. | Translational Psychiatry

Fig. 4: The relationship of serum levels of 5-HI with cortical thickness in patients with schizophrenia.

From: Effects of neuroactive metabolites of the tryptophan pathway on working memory and cortical thickness in schizophrenia

Fig. 4

The left and right frontal poles, left insula, right caudal-middle frontal, left and right lateral orbitofrontal, and right lingual areas were positively and significantly associated with 5-HI at p = 0.03–0.0003, and the right lateral occipital region was inversely associated with 5-HI at p = 0.05, but only the lateral orbitofrontal cortex (arrow) was significant after correction for multiple comparisons. A Cortical regions were colored according to t-scores by multiple linear regression. The color bar represents t-scores. B Scatter plot between 5-HI and the left lateral orbitofrontal cortex (arrow in A) in patients with schizophrenia.

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